Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6809716 | 0.86 | ESR1 (0.47) | TSHRPTPN1PTPRBACP1MEN1 | |
| SCHEMBL6809494 | 0.83 | KMT2A (0.48) | MAPTLMNAL3MBTL1PTPN1PTPRB | |
| SCHEMBL11547106 | 0.79 | SLC6A4 (0.47) | MAPTCYP3A4CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL17590423 | 0.78 | TBXA2R (0.54) | CYP3A4CYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL16839853 | 0.78 | MAPT (0.54) | MAPTCYP3A4CYP1A2CYP2C19PMP22 | |
| SCHEMBL1904599 | 0.78 | GRIN2D (0.51) | MAPTCYP3A4CYP1A2PMP22HTR2A | |
| SCHEMBL2557165 | 0.78 | CYP3A4 (0.58) | MAPTCYP3A4CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL6803905 | 0.77 | SMN1; SMN2 (0.41) | TSHRLMNANLRP3PTPN1PTPRB | |
| SCHEMBL11349337 | 0.76 | CYP3A4 (0.44) | MAPTCYP3A4CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL703931 | 0.76 | MAPT (0.72) | MAPTTSHRL3MBTL1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2604595-A1 | TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOUND THAT CONTAINS SAME AND EXHIBITS ANALGESIC ACTIVITY | Shionogi&Co., Ltd. (JP) | 2013-06-19 | — | — | EP | disclosed |