Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 18/20 | 0.58 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.58 |
| ▸ | PIK3CB | P42338 | 9/20 | 0.58 |
| ▸ | PIK3CG | P48736 | 9/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.56 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14880752 | 0.92 | PIK3CD (0.56) | PIK3CDPIK3CAPIK3CBPIK3CGKCNH2 | |
| SCHEMBL14883816 | 0.91 | PIK3CD (0.55) | PIK3CDPIK3CAPIK3CBPIK3CGKCNH2 | |
| SCHEMBL14880278 | 0.86 | PIK3CD (0.75) | PIK3CDPIK3CAPIK3CBPIK3CGKCNH2 | |
| SCHEMBL14880388 | 0.84 | PIK3CD (0.75) | PIK3CDPIK3CAPIK3CBPIK3CGKCNH2 | |
| SCHEMBL182805 | 0.83 | PIK3CD (0.58) | PIK3CDPIK3CAPIK3CBPIK3CGKCNH2 | |
| SCHEMBL14883817 | 0.82 | PIK3CD (0.62) | PIK3CDPIK3CAPIK3CBPIK3CGKCNH2 | |
| SCHEMBL14883826 | 0.80 | PIK3CD (0.53) | PIK3CDPIK3CAPIK3CBPIK3CGKCNH2 | |
| SCHEMBL182914 | 0.79 | MKNK1 (0.64) | PIK3CDPIK3CAPIK3CBPIK3CGKCNH2 | |
| SCHEMBL14880326 | 0.79 | PIK3CD (0.72) | PIK3CDPIK3CAPIK3CBPIK3CGKCNH2 | |
| SCHEMBL182967 | 0.78 | PIK3CA (0.68) | PIK3CDPIK3CAPIK3CBPIK3CGKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013088404-A1 | Use of inhibitors of the activity or function of PI3K | NOVARTIS AG (CH) | 2013-06-20 | — | — | WO | disclosed |