Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 18/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 17/20 | 0.56 |
| ▸ | PDE4A | P27815 | 16/20 | 0.56 |
| ▸ | PDE4C | Q08493 | 16/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5016433 | 0.79 | PDE4D (0.58) | PDE4DPDE4BPDE4APDE4CGFER | |
| SCHEMBL5016450 | 0.77 | PDE4D (0.57) | PDE4DPDE4BPDE4APDE4CGFER | |
| SCHEMBL4026379 | 0.76 | PDE4D (0.52) | PDE4DPDE4BPDE4APDE4CGFER | |
| SCHEMBL4027963 | 0.76 | PDE4D (0.56) | PDE4DPDE4BPDE4APDE4CGFER | |
| SCHEMBL84496 | 0.75 | PDE4D (0.53) | PDE4DPDE4BPDE4APDE4CGFER | |
| SCHEMBL4030312 | 0.75 | PDE4D (0.52) | PDE4DPDE4BPDE4APDE4CGFER | |
| SCHEMBL84495 | 0.74 | PDE4D (0.52) | PDE4DPDE4BPDE4APDE4CGFER | |
| SCHEMBL4026393 | 0.74 | PDE4D (0.55) | PDE4DPDE4BPDE4APDE4CGFER | |
| SCHEMBL8263537 | 0.74 | PDE4D (0.52) | PDE4DPDE4BPDE4APDE4CGFER | |
| SCHEMBL73542 | 0.74 | PDE4D (0.54) | PDE4DPDE4BPDE4APDE4CGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831227-B1 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS | GLENMARK PHARMACEUTICALS SA (CH) | 2013-06-19 | — | — | EP | disclosed |