Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 20/20 | 1.00 |
| ▸ | PDE4A | P27815 | 6/20 | 1.00 |
| ▸ | PDE4C | Q08493 | 6/20 | 1.00 |
| ▸ | PDE4D | Q08499 | 6/20 | 1.00 |
| ▸ | VEGFA | P15692 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5184039 | 1.00 | PDE4B (1.00) | PDE4BPDE4APDE4CPDE4DVEGFA | |
| SCHEMBL6811984 | 0.93 | PDE4B (1.00) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6811975 | 0.93 | PDE4B (1.00) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6811981 | 0.93 | PDE4B (1.00) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL5184042 | 0.86 | PDE4B (0.76) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7360513 | 0.85 | PDE4B (0.82) | PDE4BPDE4APDE4CPDE4DVEGFA | |
| SCHEMBL7365382 | 0.85 | PDE4B (0.82) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL9167416 | 0.85 | PDE4B (0.78) | PDE4BPDE4APDE4CPDE4DVEGFA | |
| SCHEMBL1572502 | 0.83 | PDE4B (0.71) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL1572976 | 0.83 | PDE4B (0.71) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831227-B1 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS | GLENMARK PHARMACEUTICALS SA (CH) | 2013-06-19 | — | — | EP | disclosed |