Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.51 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.46 |
| ▸ | S100A4 | P26447 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15040998 | 0.92 | MAPT (0.57) | MAPTNPC1RAB9APDK2HSD17B1 | |
| SCHEMBL15040977 | 0.89 | MAPT (0.53) | MAPTNPC1RAB9APDK2HSD17B1 | |
| SCHEMBL15040961 | 0.87 | MAPT (0.52) | MAPTNPC1RAB9APDK2HSD17B1 | |
| SCHEMBL15040997 | 0.84 | MAPT (0.57) | MAPTNPC1RAB9APDK2HSD17B1 | |
| SCHEMBL30705226 | 0.84 | PDK2 (0.63) | MAPTNPC1RAB9APDK2HSD17B1 | |
| SCHEMBL236472 | 0.84 | PDK2 (0.63) | MAPTNPC1RAB9APDK2HSD17B1 | |
| SCHEMBL4998169 | 0.82 | MAPT (0.47) | MAPTNPC1RAB9APDK2HSD17B1 | |
| SCHEMBL6861448 | 0.82 | MAPT (0.59) | MAPTNPC1RAB9APDK2HSD17B1 | |
| SCHEMBL5848239 | 0.82 | MAPT (0.59) | MAPTNPC1RAB9APDK2HSD17B1 | |
| SCHEMBL5056728 | 0.81 | PDK2 (0.60) | MAPTNPC1RAB9APDK2HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791275-B1 | ORGANIC SENSITIZERS FOR UP-CONVERSION | MERCK PATENT GMBH (DE) | 2017-05-31 | — | — | EP | disclosed |
| US-20140358198-A1 | ORGANIC SENSITIZERS FOR UP-CONVERSION | MERCK PATENT GMBH (DE) | 2014-12-04 | — | — | US | disclosed |
| WO-2013087162-A1 | ORGANIC SENSITIZERS FOR UP-CONVERSION | MERCK PATENT GMBH (DE) | 2013-06-20 | — | — | WO | disclosed |