Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.65 |
| ▸ | HTR2B | P41595 | 1/20 | 0.62 |
| ▸ | AHR | P35869 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15041013 | 0.89 | TTR (0.65) | TTRHTR2BAHRMEN1KMT2A | |
| SCHEMBL16714053 | 0.87 | TTR (0.84) | TTRHTR2BAHRMEN1KMT2A | |
| Silver SCHEMBL11471732 | 0.85 | TTR (0.61) | TTRHTR2BAHRMEN1KMT2A | |
| SCHEMBL7110522 | 0.85 | NPC1 (0.69) | TTRHTR2BAHRMEN1KMT2A | |
| SCHEMBL10788381 | 0.85 | TTR (0.61) | TTRHTR2BAHRMEN1KMT2A | |
| SCHEMBL29886903 | 0.85 | HTR2B (0.68) | TTRHTR2BAHRMEN1KMT2A | |
| SCHEMBL11471734 | 0.85 | TTR (0.81) | TTRHTR2BAHRMEN1KMT2A | |
| SCHEMBL6202281 | 0.84 | TTR (0.59) | TTRHTR2BMEN1KMT2AALDH1A1 | |
| SCHEMBL22146687 | 0.83 | TTR (0.55) | TTRHTR2BAHRMEN1KMT2A | |
| SCHEMBL26304441 | 0.82 | NPC1 (0.65) | TTRHTR2BAHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791275-B1 | ORGANIC SENSITIZERS FOR UP-CONVERSION | MERCK PATENT GMBH (DE) | 2017-05-31 | — | — | EP | disclosed |
| US-20140358198-A1 | ORGANIC SENSITIZERS FOR UP-CONVERSION | MERCK PATENT GMBH (DE) | 2014-12-04 | — | — | US | disclosed |
| US-20140358198-A1 | ORGANIC SENSITIZERS FOR UP-CONVERSION | MERCK PATENT GMBH (DE) | 2014-12-04 | — | — | US | disclosed |
| WO-2013087162-A1 | ORGANIC SENSITIZERS FOR UP-CONVERSION | MERCK PATENT GMBH (DE) | 2013-06-20 | — | — | WO | disclosed |