Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 5/20 | 0.53 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15014364 | 0.81 | ESR2 (0.53) | ESR2EGLN1EGLN3GRM5HRH3 | |
| SCHEMBL10091187 | 0.81 | ESR2 (0.53) | ESR2GRM5FFAR1 | |
| SCHEMBL11196166 | 0.79 | ESR2 (0.77) | ESR2POLBDRD2ESR1CYP3A4 | |
| SCHEMBL13226083 | 0.79 | ESR2 (0.50) | ESR2EGLN1EGLN3GRM5HRH3 | |
| SCHEMBL9548930 | 0.78 | CYP2C9 (0.52) | ESR2DRD2ESR1CYP3A4CYP2C9 | |
| SCHEMBL9548931 | 0.78 | CYP2C9 (0.52) | ESR2DRD2ESR1CYP3A4CYP2C9 | |
| SCHEMBL15043572 | 0.77 | ESR2 (0.49) | ESR2EGLN1EGLN3GRM5HRH3 | |
| SCHEMBL13433641 | 0.77 | APP (0.49) | ESR2DRD2KCNH2 | |
| SCHEMBL9508933 | 0.77 | APP (0.49) | ESR2DRD2KCNH2 | |
| SCHEMBL20083485 | 0.77 | ESR2 (0.57) | ESR2HRH3GRIA1GRIA2GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617473-B2 | Switch element comprising a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-04-11 | — | — | US | disclosed |
| US-9617473-B2 | Switch element comprising a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-04-11 | — | — | US | disclosed |
| US-20130155338-A1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-06-20 | — | — | US | disclosed |