Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PTGIR | P43119 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10056850 | 0.88 | CYP2D6 (0.43) | TDP1CYP2D6 | |
| SCHEMBL15044119 | 0.87 | TDP1 (0.33) | TDP1PTGIRKMT2A | |
| SCHEMBL15044280 | 0.80 | TDP1 (0.46) | TDP1PTGIRCYP2D6 | |
| SCHEMBL15044064 | 0.79 | TDP1 (0.39) | TDP1PTGIRCYP2D6KMT2A | |
| SCHEMBL27393650 | 0.67 | TDP1 (0.45) | TDP1KMT2A | |
| SCHEMBL12631990 | 0.66 | GABRR1 (0.35) | KMT2A | |
| SCHEMBL3271679 | 0.66 | GABRR1 (0.35) | KMT2A | |
| SCHEMBL10055215 | 0.66 | SMN1; SMN2 (0.46) | TDP1KMT2A | |
| SCHEMBL10056848 | 0.65 | CYP2D6 (0.47) | TDP1CYP2D6 | |
| SCHEMBL18889628 | 0.65 | TDP1 (0.44) | TDP1CYP2D6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013089212-A1 | SUBSTITUTED TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 塩野義製薬株式会社 (JP) | 2013-06-20 | — | — | WO | disclosed |