SCHEMBL150450

SCHEMBL150450

CO[SiH2]CCCOCC1CO1

nearest known ligand 0.61

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.61
SMN1; SMN2 Q16637 1/20 0.58
ALDH1A1 P00352 5/20 0.55
TDP1 Q9NUW8 1/20 0.55
MAPK1 P28482 1/20 0.41
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5522882 1.00 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL9869829 0.95 TSHR (0.64) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
Diethylamine SCHEMBL27850038 0.91 SMN1; SMN2 (0.53) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL4925410 0.89 TSHR (0.54) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL11896227 0.86 TSHR (0.53) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL7215607 0.86 TSHR (0.57) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL17727830 0.85 TSHR (0.65) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL7629065 0.82 TSHR (0.57) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL3797904 0.82 SMN1; SMN2 (0.59) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL28491004 0.82 TSHR (0.42) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 779 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116216931-B Preparation method and application of denitrification solid slow-release carbon source 中国科学院南京地理与湖泊研究所 2024-08-20 CN claimed
CN-114836041-B Composite insulator rubber compound and preparation method and application thereof 山东泰开电器绝缘有限公司 2024-05-07 CN claimed
CN-117299098-B High-performance titanium-based lithium adsorbent and preparation method and application thereof 万华化学集团股份有限公司 2024-02-27 CN claimed
CN-117299098-A High-performance titanium-based lithium adsorbent and preparation method and application thereof 万华化学集团股份有限公司 2023-12-29 CN claimed
CN-114774063-B Packaging adhesive for OLED flexible display screen and preparation method thereof 烟台万华聚氨酯合成材料有限公司 2023-06-09 CN claimed
CN-116216931-A Preparation method and application of denitrification solid slow-release carbon source 中国科学院南京地理与湖泊研究所 2023-06-06 CN claimed
CN-114836041-A Composite insulator rubber compound and preparation method and application thereof 山东泰开电器绝缘有限公司 2022-08-02 CN claimed
CN-110951080-B Composition containing 3-glycidoxypropylalkoxysilane oligomer, method for producing same and use thereof 赢创运营有限公司 2022-07-05 CN claimed
EP-3628700-B1 3-GLYCIDYLOXYPROPYLALKOXYSILANE OLIGOMER-CONTAINING COMPOSITION, METHOD FOR THEIR PREPARATION AND THEIR USE EVONIK OPERATIONS GMBH (DE) 2022-06-01 EP claimed
CN-114196207-A Phenyl silicone rubber compound for composite insulator and preparation method and application thereof 山东大学 2022-03-18 CN claimed
EP-2414467-A1 WATER BASED NON-CHROMATED PRIMERS FOR STRUCTURAL BONDING APPLICATIONS CYTEC TECHNOLOGY CORP. (US) 2012-02-08 EP claimed
WO-2010117757-A1 WATER BASED NON-CHROMATED PRIMERS FOR STRUCTURAL BONDING APPLICATIONS CYTEC TECHNOLOGY CORP. (US) 2010-10-14 WO claimed
US-20100247922-A1 Water Based Non-Chromated Primers for Structural Bonding Applications CYTEC TECHNOLOGY CORP. (US) 2010-09-30 US claimed
EP-1907494-A2 ORGANIC-INORGANIC HYBRID COATINGS Sheffield Hallam University (GB) 2008-04-09 EP claimed
WO-2006120390-A2 ORGANIC-INORGANIC HYBRID COATINGS SHEFFIELD HALLAM UNIVERSITY (GB) 2006-11-16 WO claimed
US-6749946-B1 Method and composition for metallic finishes LACKS ENTERPRISES, INC. 2004-06-15 US claimed
US-5552459-A FLAME RETARDANT CIBA-GEIGY CORPORATION (US) 1996-09-03 US claimed
US-4729771-A POLYIMIDE MATRIX, ABRASIVE PARTICLES UBE INDUSTRIES, LTD. (JP) 1988-03-08 US claimed
US-4689163-A IRON-BORON-NEODYMIUM OR PRASEODYMIUM, URETHANE MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1987-08-25 US claimed
US-4148637-A Silane coupling agent in protective layer of photoconductive element RICOH CO., LTD. (JP) 1979-04-10 US claimed