Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 0.60 |
| ▸ | F2 | P00734 | 4/20 | 0.50 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.47 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.46 |
| ▸ | PYGL | P06737 | 4/20 | 0.46 |
| ▸ | PYGM | P11217 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1858290 | 1.00 | F10 (0.60) | F10F2SMYD3NHERF1PYGL | |
| SCHEMBL2943091 | 1.00 | F10 (0.60) | F10F2SMYD3NHERF1PYGL | |
| SCHEMBL2943094 | 1.00 | F10 (0.60) | F10F2SMYD3NHERF1PYGL | |
| SCHEMBL11888298 | 0.90 | F10 (0.61) | F10F2SMYD3NHERF1PYGL | |
| SCHEMBL1857646 | 0.86 | F10 (0.60) | F10F2SMYD3NHERF1PYGL | |
| SCHEMBL2935412 | 0.86 | F10 (0.60) | F10F2SMYD3NHERF1PYGL | |
| SCHEMBL1857642 | 0.86 | F10 (0.60) | F10F2SMYD3NHERF1PYGL | |
| SCHEMBL12669925 | 0.84 | F10 (0.71) | F10F2SMYD3NHERF1PYGL | |
| SCHEMBL11888229 | 0.81 | F10 (0.61) | F10F2SMYD3NHERF1PYGL | |
| SCHEMBL765293 | 0.80 | F10 (0.62) | F10F2SMYD3NHERF1PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2431370-B1 | Monoacylated 1,2-diaminocycloalkanes | DAIICHI SANKYO CO LTD (JP) | 2013-06-19 | — | — | EP | disclosed |