SCHEMBL15045544

SCHEMBL15045544

C[Si](C)(C)O[Si](C)(C)CCCCCCCCOc1ccc(-c2ccc(C#N)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.50
ALDH1A1 P00352 2/20 0.50
HPGD P15428 2/20 0.50
HTT P42858 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
HDAC1 Q13547 1/20 0.50
HDAC2 Q92769 1/20 0.50
MMP3 P08254 5/20 0.48
HRH3 Q9Y5N1 11/20 0.47
HRH2 P25021 8/20 0.47
HRH1 P35367 8/20 0.47
MMP2 P08253 4/20 0.47
MMP1 P03956 1/20 0.44
MMP9 P14780 1/20 0.44
MMP13 P45452 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17225149 1.00 KDM4E (0.50) KDM4EALDH1A1HPGDHTTL3MBTL1
SCHEMBL20646107 0.89 KDM4E (0.61) KDM4EALDH1A1HPGDHTTL3MBTL1
SCHEMBL13110640 0.89 KDM4E (0.48) KDM4EALDH1A1HPGDHTTL3MBTL1
SCHEMBL20646098 0.87 KDM4E (0.70) KDM4EALDH1A1HPGDHTTL3MBTL1
SCHEMBL20646109 0.87 KDM4E (0.43) KDM4EALDH1A1HPGDHTTL3MBTL1
SCHEMBL20646112 0.86 KDM4E (0.40) KDM4EALDH1A1HPGDHTTL3MBTL1
SCHEMBL20646108 0.85 HRH3 (0.50) KDM4EALDH1A1HPGDL3MBTL1HRH3
SCHEMBL13610333 0.84 KDM4E (0.46) KDM4EALDH1A1HPGDHTTL3MBTL1
SCHEMBL8915948 0.84 HDAC1 (0.45) HDAC1HDAC2MMP3MMP2MMP1
SCHEMBL5089722 0.84 KDM4E (0.48) KDM4EALDH1A1HPGDHTTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110199007-B Non-linear side chain liquid crystalline polyorganosiloxanes, method for the production thereof and use thereof in electro-optical applications and devices 美国陶氏有机硅公司 2023-02-28 CN disclosed
US-11001758-B2 Non-linear side chain liquid crystal polyorganosiloxanes and methods for their preparation and use in electro-optic applications and devices DOW SILICONES CORPORATION (US) 2021-05-11 US disclosed
US-20190144752-A1 NON-LINEAR SIDE CHAIN LIQUID CRYSTAL POLYORGANOSILOXANES AND METHODS FOR THEIR PREPARATION AND USE IN ELECTRO-OPTIC APPLICATIONS AND DEVICES DOW CORNING (US) 2019-05-16 US disclosed
WO-2017213809-A1 NON-LINEAR SIDE CHAIN LIQUID CRYSTAL POLYORGANOSILOXANES AND METHODS FOR THEIR PREPARATION AND USE IN ELECTRO-OPTIC APPLICATIONS AND DEVICES DOW CORNING CORPORATION (US) 2017-12-14 WO disclosed
EP-2894148-A1 NOVEL SMECTIC PHASE A LIQUID CRYSTAL MATERIAL Halation Photonics Corporation (CN) 2015-07-15 EP disclosed
US-8956548-B2 Liquid crystal formulations and structures for smectic A optical devices DOW CORNING CORPORATION (US) 2015-02-17 US disclosed
US-8956548-B2 Liquid crystal formulations and structures for smectic A optical devices DOW CORNING CORPORATION (US) 2015-02-17 US disclosed
US-20140160384-A1 SMECTIC A-PHASE LIQUID CRYSTAL MATERIAL HALATION PHOTONICS CORPORATION (CN) 2014-06-12 US disclosed
US-20130155340-A1 Liquid Crystal Formulations And Structures For Smectic A Optical Devices DOW SILICONES CORPORATION 2013-06-20 US disclosed
US-20130155340-A1 Liquid Crystal Formulations And Structures For Smectic A Optical Devices DOW SILICONES CORPORATION 2013-06-20 US disclosed