Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL16568230 | 0.95 | FGFR1 (0.90) | FGFR1 | |
| SCHEMBL15045727 | 0.93 | FGFR1 (1.00) | FGFR1 | |
| SCHEMBL15045670 | 0.89 | FGFR1 (1.00) | FGFR1 | |
| Hydrochloric Acid SCHEMBL16568507 | 0.89 | FGFR1 (0.98) | FGFR1 | |
| SCHEMBL15045652 | 0.89 | FGFR1 (1.00) | FGFR1 | |
| SCHEMBL15019449 | 0.88 | FGFR1 (1.00) | FGFR1 | |
| SCHEMBL15045671 | 0.88 | FGFR1 (1.00) | FGFR1 | |
| Hydrochloric Acid SCHEMBL16568552 | 0.87 | FGFR1 (0.98) | FGFR1 | |
| SCHEMBL16568233 | 0.87 | FGFR1 (0.77) | FGFR1 | |
| SCHEMBL15045662 | 0.86 | FGFR1 (1.00) | FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9598416-B2 | Substituted benzothienyl-pyrrolotriazines and uses thereof in the treatment cancer | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-03-21 | — | — | US | disclosed |
| EP-2791143-B1 | SUBSTITUTED BENZOTHIENYL-PYRROLOTRIAZINES AND USES THEREOF IN THE TREATMENT OF CANCER | BAYER IP GMBH (DE) | 2016-02-24 | — | — | EP | disclosed |
| WO-2013087647-A1 | SUBSTITUTED BENZOTHIENYL - PYRROLOTRIAZINES AND USES THEREOF IN THE TREATMENT CANCER | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-06-20 | — | — | WO | disclosed |