Chlormadinone Acetate

Chlormadinone Acetate

SCHEMBL15046

CC(=O)O[C@]1(C(C)=O)CC[C@H]2[C@@H]3C=C(Cl)C4=CC(=O)CC[C@]4(C)[C@H]3CC[C@@]21C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

PGR

The experimentally established mechanism targets of Chlormadinone Acetate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR known ✓ P06401 7/20 1.00
AR P10275 7/20 1.00
CYP3A4 P08684 7/20 1.00
NR3C1 P04150 7/20 1.00
SMN1; SMN2 Q16637 5/20 1.00
NPSR1 Q6W5P4 4/20 1.00
MAPK1 P28482 3/20 1.00
HIF1A Q16665 3/20 1.00
ALDH1A1 P00352 3/20 1.00
CHRM2 P08172 3/20 1.00
CHRM1 P11229 3/20 1.00
USP2 O75604 2/20 1.00
ADORA3 P0DMS8 2/20 1.00
THRB P10828 1/20 1.00
TBXA2R P21731 1/20 1.00
CYP2C19 P33261 1/20 1.00
ADRA1A P35348 1/20 1.00
LMNA P02545 6/20 0.80
MEN1 O00255 4/20 0.80
KMT2A Q03164 4/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlormadinone Acetate SCHEMBL29430402 1.00 AR (1.00) ARCYP3A4NR3C1PGRSMN1; SMN2
Chlormadinone Acetate SCHEMBL11795531 1.00 AR (1.00) ARCYP3A4NR3C1PGRSMN1; SMN2
Chlormadinone Acetate SCHEMBL40360 1.00 AR (1.00) ARCYP3A4NR3C1PGRSMN1; SMN2
Chlormadinone Acetate SCHEMBL1460594 1.00 AR (1.00) ARCYP3A4NR3C1PGRSMN1; SMN2
Chlormadinone Acetate SCHEMBL4948575 1.00 AR (1.00) ARCYP3A4NR3C1PGRSMN1; SMN2
Chlormadinone Acetate SCHEMBL1460593 1.00 AR (1.00) ARCYP3A4NR3C1PGRSMN1; SMN2
Chlormadinone Acetate SCHEMBL23908022 0.99 AR (0.98) ARCYP3A4NR3C1PGRSMN1; SMN2
Chlormadinone Acetate SCHEMBL1250000 0.90 AR (0.82) ARCYP3A4NR3C1PGRSMN1; SMN2
Chlormadinone Acetate SCHEMBL9572032 0.90 CYP3A4 (0.80) ARCYP3A4NR3C1PGRSMN1; SMN2
SCHEMBL11512932 0.89 AR (0.81) ARCYP3A4NR3C1PGRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 10737 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4440706-B1 COMPOSITIONS FOR PROMOTING HAIR GROWTH ESTETRA SRL (BE) 2026-04-29 EP claimed
EP-4530869-B1 MEMORY DEVICE, CXL MEMORY DEVICE, SYSTEM IN PACKAGE, AND SYSTEM ON CHIP INCLUDING HIGH BANDWIDTH MEMORY SAMSUNG ELECTRONICS CO LTD (KR) 2026-04-22 EP claimed
EP-4525938-B1 RADIOPHARMACEUTICAL COMPLEXES TARGETING PROSTATE-SPECIFIC MEMBRANE ANTIGEN AND ITS COMBINATIONS BAYER AG (DE) 2026-03-11 EP claimed
US-20260053736-A1 LONG ACTING DRUG DELIVERY DEVICE AND ITS USE IN CONTRACEPTION BAYER OY (FI) 2026-02-26 US claimed
EP-4463570-B1 METHOD FOR HORMONE OR DRUG SCREENING IN A TISSUE SAMPLE ECOLE POLYTECHNIQUE FED LAUSANNE EPFL (CH) 2026-01-14 EP claimed
EP-4643858-A1 METHODS AND PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF UTERINE DISEASE Institut National de la Santé et de la Recherche Médicale (FR) 2025-11-05 EP claimed
EP-4638443-A1 TRANSIENT RECEPTOR POTENTIAL VANILLOID 6 INHIBITORS Uniquest Pty Limited (AU) 2025-10-29 EP claimed
US-20250319216-A1 RADIOPHARMCEUTICAL COMPLEXES TARGETING PROSTATE-SPECIFIC MEMBRANE ANTIGEN AND ITS COMBINATIONS BAYER AG (DE) 2025-10-16 US claimed
EP-3691331-B1 METHOD FOR TRANSMITTING CONTROL AND TRAINING SYMBOLS IN MULTI-USER WIRELESS COMMUNICATION SYSTEM ELECTRONICS & TELECOMMUNICATIONS RES INST (KR) 2025-09-17 EP claimed
EP-4608405-A1 COMPOSITIONS AND METHODS OF USE FOR MODIFIED RELEASE MINOXIDIL Veradermics, Incorporated (US) 2025-09-03 EP claimed
EP-0122419-A2 Substituted 3-mercaptopyridazines, their 3-alkylthio derivatives and processes for their preparation A. Nattermann & Cie. GmbH (DE) 1984-10-24 EP claimed
EP-0121088-A1 New o-acyl-alkanediol-phospholipids, processes for their preparation and pharmaceutical preparations containing them A. Nattermann & Cie. GmbH (DE) 1984-10-10 EP claimed
US-4394731-A Cache storage line shareability control for a multiprocessor system INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1983-07-19 US claimed
US-4346709-A Drug delivery devices comprising erodible polymer and erosion rate modifier ALZA CORPORATION (US) 1982-08-31 US claimed
EP-0051829-A1 N-substituted omega-(2-oxo-4-imidazolin-1-yl) alcanoic acids, salts and esters thereof, process for producing the same and these active agents containing pharmaceutical compounds A. Nattermann & Cie. GmbH (DE) 1982-05-19 EP claimed
US-4310523-A Combined antiestrogens and antigonadotropically effective antiandrogens for the prophylaxis and therapy of hyperplasia of the prostate SCHERING AKTIENGESELLSCHAFT (DE) 1982-01-12 US claimed
US-4171358-A ADMINISTERING PROGESTATIONAL AGENTS ELI LILLY AND COMPANY (US) 1979-10-16 US claimed
US-4018919-A IN MAMMALS ELI LILLY AND COMPANY (US) 1977-04-19 US claimed
US-4016270-A Method for treating dysmenorrhea with a uterine therapeutic system ALZA CORPORATION (US) 1977-04-05 US claimed
US-4014988-A Method for treating hypermenorrhea with uterine therapeutic system ALZA CORPORATION (US) 1977-03-29 US claimed