Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 3/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.60 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.60 |
| ▸ | POLA1 | P09884 | 2/20 | 0.52 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.38 |
| ▸ | ALB | P02768 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | POLG | P54098 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15045976 | 0.88 | PDE3A (0.60) | PDE3APDE4DSLC29A1POLA1NT5E | |
| SCHEMBL23474279 | 0.88 | PDE3A (0.65) | PDE3APDE4DSLC29A1POLA1NT5E | |
| SCHEMBL25619493 | 0.88 | PDE3A (0.65) | PDE3APDE4DSLC29A1POLA1NT5E | |
| SCHEMBL23474183 | 0.88 | PDE3A (0.65) | PDE3APDE4DSLC29A1POLA1NT5E | |
| SCHEMBL15253010 | 0.88 | PDE3A (0.65) | PDE3APDE4DSLC29A1POLA1NT5E | |
| SCHEMBL13190275 | 0.87 | PDE3A (0.57) | PDE3APDE4DSLC29A1POLA1NT5E | |
| SCHEMBL13134656 | 0.87 | PDE3A (0.57) | PDE3APDE4DSLC29A1POLA1NT5E | |
| SCHEMBL800384 | 0.87 | PDE3A (0.57) | PDE3APDE4DSLC29A1POLA1NT5E | |
| SCHEMBL882023 | 0.86 | PDE3A (0.56) | PDE3APDE4DSLC29A1POLA1NT5E | |
| SCHEMBL800826 | 0.85 | PDE3A (0.57) | PDE3APDE4DSLC29A1POLA1NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013090420-A2 | FATTY ACID ANTIVIRAL CONJUGATES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. (US) | 2013-06-20 | — | — | WO | disclosed |