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SCHEMBL15046277

SCHEMBL15046277

CC(C)(C)c1ccc(N2c3ccccc3C(C)(C)c3cc4c(cc32)C(C)(C)c2cc(/C=C/c3ccc5cc(-c6ccc7c(c6)C(C)(C)c6cc8c(cc6-7)C(C)(C)c6ccccc6N8c6ccccc6)ccc5c3)ccc2-4)cc1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ NR1H2 P55055 1/20 0.35
▸ NR1H3 Q13133 1/20 0.35
▸ PDK2 Q15119 1/20 0.30
▸ TRPV1 Q8NER1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15046344 1.00 NR1H2 (0.35) NR1H2NR1H3PDK2TRPV1
SCHEMBL15046416 0.97 NR1H2 (0.36) NR1H2NR1H3PDK2TRPV1
SCHEMBL15046253 0.97 NR1H2 (0.36) NR1H2NR1H3PDK2TRPV1
SCHEMBL15046321 0.95 NR1H2 (0.34) NR1H2NR1H3
SCHEMBL15046239 0.94 NR1H2 (0.39) NR1H2NR1H3PDK2TRPV1
SCHEMBL15046250 0.94 NR1H2 (0.39) NR1H2NR1H3PDK2TRPV1
SCHEMBL15046257 0.93 PDK2 (0.32) PDK2
SCHEMBL15046420 0.92 NR1H2 (0.40) NR1H2NR1H3PDK2
SCHEMBL15046355 0.91 NR1H2 (0.39) NR1H2NR1H3PDK2
SCHEMBL15046390 0.90 NR1H2 (0.33) NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013089460-A1 NOVEL CHEMICAL COMPOUND HAVING AN ACRIDINE STRUCTURE, AND ORGANIC LIGHT-EMITTING DIODE USING SAME 주식회사 두산 (KR) 2013-06-20 — — WO disclosed
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