⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28023969 | 0.72 | — | — | |
| SCHEMBL24752798 | 0.69 | — | — | |
| SCHEMBL4252731 | 0.69 | — | — | |
| SCHEMBL28871573 | 0.67 | HIF1A (0.30) | — | |
| Hydrochloric Acid SCHEMBL27272203 | 0.67 | — | — | |
| SCHEMBL28274261 | 0.65 | — | — | |
| SCHEMBL17641533 | 0.64 | — | — | |
| SCHEMBL4173882 | 0.64 | — | — | |
| SCHEMBL391539 | 0.64 | — | — | |
| SCHEMBL17641532 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2604610-A1 | PHTHALAZINONE KETONE DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL USE THEREOF | Jiangsu Hansoh Pharmaceutical Co., Ltd. (CN) | 2013-06-19 | — | — | EP | disclosed |