Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 20/20 | 0.76 |
| ▸ | FGFR3 | P22607 | 16/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15047986 | 0.88 | FGFR1 (0.80) | FGFR1FGFR3 | |
| SCHEMBL15023980 | 0.87 | FGFR1 (0.76) | FGFR1FGFR3 | |
| SCHEMBL15023381 | 0.86 | FGFR1 (1.00) | FGFR1FGFR3 | |
| SCHEMBL15020408 | 0.86 | FGFR1 (0.84) | FGFR1FGFR3 | |
| SCHEMBL15023095 | 0.85 | FGFR1 (1.00) | FGFR1FGFR3 | |
| SCHEMBL15020378 | 0.82 | FGFR1 (1.00) | FGFR1FGFR3 | |
| SCHEMBL15019843 | 0.79 | FGFR1 (0.72) | FGFR1FGFR3 | |
| SCHEMBL16577572 | 0.78 | FGFR1 (0.71) | FGFR1FGFR3 | |
| SCHEMBL15023094 | 0.78 | FGFR1 (1.00) | FGFR1FGFR3 | |
| SCHEMBL15023384 | 0.78 | FGFR1 (1.00) | FGFR1FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013087578-A1 | DISUBSTITUTED BENZOTHIENYL-PYRROLOTRIAZINES AND THEIR USE AS FGFR KINASE INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2013-06-20 | — | — | WO | disclosed |