Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 16/20 | 0.66 |
| ▸ | KDR | P35968 | 15/20 | 0.66 |
| ▸ | AURKA | O14965 | 8/20 | 0.62 |
| ▸ | AURKB | Q96GD4 | 8/20 | 0.62 |
| ▸ | TEK | Q02763 | 6/20 | 0.62 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.62 |
| ▸ | BRAF | P15056 | 3/20 | 0.61 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.58 |
| ▸ | FLT4 | P35916 | 4/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1504816 | 0.94 | EGFR (0.67) | EGFRKDRAURKAAURKBTEK | |
| SCHEMBL1504960 | 0.91 | EGFR (0.69) | EGFRKDRAURKAAURKBTEK | |
| SCHEMBL12507381 | 0.90 | EGFR (0.67) | EGFRKDRAURKAAURKBTEK | |
| SCHEMBL2189087 | 0.90 | KDR (0.71) | EGFRKDRAURKAAURKBTEK | |
| SCHEMBL1505015 | 0.89 | EGFR (0.70) | EGFRKDRAURKAAURKBTEK | |
| SCHEMBL1504997 | 0.88 | EGFR (0.70) | EGFRKDRAURKAAURKBTEK | |
| SCHEMBL3948194 | 0.88 | EGFR (0.68) | EGFRKDRAURKAAURKBTEK | |
| SCHEMBL3947514 | 0.88 | EGFR (0.65) | EGFRKDRAURKAAURKBTEK | |
| SCHEMBL3946804 | 0.88 | EGFR (0.78) | EGFRKDRAURKAAURKBTEK | |
| SCHEMBL3944918 | 0.87 | KDR (0.64) | EGFRKDRAURKAAURKBTEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011033094-A1 | SCHEDULE OF ADMINISTRATION OF BENZAZOLE DERIVATIVES IN THE TREATMENT OF LEUKEMIAS | 4SC AG (DE) | 2011-03-24 | — | — | WO | claimed |