SCHEMBL150495

SCHEMBL150495

O=C1NCNN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7608614 0.97
SCHEMBL530409 0.73
SCHEMBL19760059 0.72 CRBN (0.38)
SCHEMBL2172985 0.67
SCHEMBL1411120 0.67
SCHEMBL8490586 0.60
SCHEMBL8394035 0.60
SCHEMBL9389771 0.58
SCHEMBL17067280 0.58
SCHEMBL9051900 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240368092-A1 2,4-Dihydro-3H-1,2,4-Triazol-3-One P2X7 Antagonists BREYE THERAPEUTICS APS (DK) 2024-11-07 US claimed
CN-113004186-B Zinc-ligand azapyrrolidone photo-diagnosis and treatment reagent with long-wave absorption characteristic and preparation and application thereof 南京邮电大学 2022-12-30 CN claimed
EP-3099678-B1 NEPRILYSIN INHIBITORS THERAVANCE BIOPHARMA R&D IP LLC (US) 2018-12-12 EP claimed
US-6991659-B2 Production of tanned leather and products suitable therefore CLARIANT FINANCE (BVI) LIMITED (VG) 2006-01-31 US claimed
EP-1362128-B1 PRODUCTION OF TANNED LEATHER AND PRODUCTS SUITABLE THEREFORE CLARIANT FINANCE BVI LTD (VG) 2005-03-09 EP claimed
US-20040074009-A1 Production of tanned leather and products suitable therefore CLARIANT FINANCE (BVI) LIMITED (VG) 2004-04-22 US claimed
EP-1362128-A1 PRODUCTION OF TANNED LEATHER AND PRODUCTS SUITABLE THEREFORE Clariant Finance (BVI) Limited (VG) 2003-11-19 EP claimed
JP-2002528505-A 2002-09-03 JP claimed
WO-2002059382-A1 PRODUCTION OF TANNED LEATHER AND PRODUCTS SUITABLE THEREFORE CLARIANT INTERNATIONAL LTD (CH) 2002-08-01 WO claimed
EP-1126853-A1 CONTROLLED DELIVERY OF ANTIDEPRESSANTS ALZA CORPORATION (US) 2001-08-29 EP claimed
WO-2000025790-A1 CONTROLLED DELIVERY OF ANTIDEPRESSANTS ALZA CORPORATION (US) 2000-05-11 WO claimed
JP-9216881-A None JP disclosed
US-12344597-B2 Alkoxy-substituted pyridinyl derivatives as LPA1 receptor antagonists and their use in the treatment of fibrosis IDORSIA PHARMACEUTICALS LTD (CH) 2025-07-01 US disclosed
WO-2025133078-A1 VIRAL PROTEASE INHIBITORS WITH A HYDROXYBENZYL ALCOHOL WARHEAD STICHTING RADBOUD UNIVERSITEIT (NL) 2025-06-26 WO disclosed
US-20250179061-A1 RIP1 MODULATORS, PREPARATIONS, AND USES THEREOF Sironax Ltd. (KY) 2025-06-05 US disclosed
WO-1987003782-A1 HERBICIDAL ARYL TRIAZOLINONES FMC CORPORATION (US) 1987-07-02 WO disclosed
EP-0039421-B1 1-(TRIHALOGEN-METHYL-SULFONYL)-4-ARYL-1,2,4-TRIAZOLIDIN-5-ONES, PROCESS FOR THEIR PREPARATION, FUNGICIDES CONTAINING THEM AND PROCESS FOR COMBATING FUNGI WITH THESE PRODUCTS BASF Aktiengesellschaft (DE) 1983-11-02 EP disclosed
US-4350701-A 1-(Trihalomethyl-sulfenyl)-4-aryl-1,2,4-triazolin-5-ones, and process for controlling fungi BASF AKTIENGESELLSCHAFT (DE) 1982-09-21 US disclosed
US-4139363-A REACTION OF THIONYL CHLORIDE AND A SEMICARBAZIDE CHEVRON RESEARCH COMPANY (US) 1979-02-13 US disclosed
US-4110332-A PESTICIDES CHEVRON RESEARCH COMPANY (US) 1978-08-29 US disclosed