Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | KLKB1 | P03952 | 17/20 | 0.55 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1049941 | 0.90 | GAA (0.56) | GAAKLKB1DGAT1 | |
| SCHEMBL2361709 | 0.89 | GAA (0.54) | GAAKLKB1DGAT1 | |
| SCHEMBL3355699 | 0.89 | GAA (0.54) | GAAKLKB1DGAT1 | |
| SCHEMBL7980023 | 0.88 | KLKB1 (0.60) | GAAKLKB1DGAT1 | |
| SCHEMBL20521837 | 0.88 | GAA (0.53) | GAAKLKB1DGAT1 | |
| SCHEMBL3356363 | 0.86 | GAA (0.51) | GAAKLKB1DGAT1 | |
| SCHEMBL14150628 | 0.83 | KLKB1 (0.48) | GAAKLKB1DGAT1 | |
| SCHEMBL1048741 | 0.83 | KLKB1 (0.48) | GAAKLKB1DGAT1 | |
| SCHEMBL371016 | 0.82 | KMT2A (0.46) | GAA | |
| SCHEMBL14823853 | 0.82 | KMT2A (0.46) | GAAKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2456769-B1 | NOVEL PYRAZOLE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ADDEX PHARMA SA (CH) | 2013-06-26 | — | — | EP | disclosed |