Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15058009 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1EPHX1TSHRCYP3A4 | |
| SCHEMBL3054649 | 0.97 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1EPHX1TSHRCYP3A4 | |
| SCHEMBL3054655 | 0.97 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1EPHX1TSHRCYP3A4 | |
| SCHEMBL15058144 | 0.95 | EPHX1 (0.53) | SMN1; SMN2ALDH1A1EPHX1TSHRCYP3A4 | |
| SCHEMBL8682268 | 0.95 | EPHX1 (0.53) | SMN1; SMN2ALDH1A1EPHX1TSHRCYP3A4 | |
| SCHEMBL2595920 | 0.85 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1EPHX1TSHRCYP3A4 | |
| SCHEMBL2595916 | 0.85 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1EPHX1TSHRCYP3A4 | |
| SCHEMBL8204925 | 0.84 | EPHX1 (0.47) | SMN1; SMN2ALDH1A1EPHX1TSHRCYP3A4 | |
| SCHEMBL14975219 | 0.83 | EPHX1 (0.51) | SMN1; SMN2ALDH1A1EPHX1TSHRCYP3A4 | |
| SCHEMBL889324 | 0.83 | EPHX1 (0.46) | SMN1; SMN2ALDH1A1EPHX1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013095275-A1 | NOVEL HEPATITIS C VIRUS INHIBITORS | MEDIVIR AB (SE) | 2013-06-27 | — | — | WO | disclosed |