Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.50 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 7/20 | 0.48 |
| ▸ | PPARD | Q03181 | 7/20 | 0.48 |
| ▸ | PPARA | Q07869 | 7/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15058713 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL18419645 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL760043 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL15058054 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL15058127 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL15058968 | 0.86 | FFAR4 (0.59) | TSHRLMNANFKB1PMP22FFAR1 | |
| SCHEMBL15058597 | 0.85 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL15361928 | 0.85 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL18419647 | 0.85 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL758780 | 0.85 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2827829-B1 | PEG-FREE ANTIPERSPIRANT OIL-IN-WATER EMULSIONS HAVING IMPROVED FEEL | HENKEL AG & CO KGAA (DE) | 2017-02-08 | — | — | EP | disclosed |
| EP-2827829-A2 | PEG-FREE ANTIPERSPIRANT OIL-IN-WATER EMULSIONS HAVING IMPROVED FEEL | Henkel AG & Co. KGaA (DE) | 2015-01-28 | — | — | EP | disclosed |
| WO-2013092186-A2 | PEG-FREE ANTIPERSPIRANT OIL-IN-WATER EMULSIONS HAVING IMPROVED FEEL | HENKEL AG & CO. KGAA (DE) | 2013-06-27 | — | — | WO | disclosed |