Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 8/20 | 0.67 |
| ▸ | MAOB | P27338 | 4/20 | 0.67 |
| ▸ | MAOA | P21397 | 2/20 | 0.67 |
| ▸ | SYK | P43405 | 1/20 | 0.50 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.48 |
| ▸ | CDK2 | P24941 | 4/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.48 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.48 |
| ▸ | CDK1 | P06493 | 2/20 | 0.48 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.48 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.48 |
| ▸ | CCND3 | P30281 | 1/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | CDK9 | P50750 | 1/20 | 0.48 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.48 |
| ▸ | PLK1 | P53350 | 3/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | BCR | P11274 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11297563 | 0.84 | GRM5 (0.65) | GRM5MAOBMAOASYKCCNA2 | |
| SCHEMBL9955475 | 0.81 | GRM5 (1.00) | GRM5MAOBMAOASYKCCNA2 | |
| SCHEMBL9960032 | 0.80 | GRM5 (1.00) | GRM5MAOBMAOASYKCCNA2 | |
| SCHEMBL23657061 | 0.78 | GRM5 (0.95) | GRM5MAOBMAOASYKCCNA2 | |
| SCHEMBL7238444 | 0.73 | FYN (0.58) | GRM5MAOBCCNA2CDK2CDK5 | |
| SCHEMBL15058984 | 0.73 | GRM5 (0.53) | GRM5MAOBMAOASYKCCNA2 | |
| SCHEMBL1185063 | 0.72 | PLK1 (0.86) | PLK1 | |
| SCHEMBL11294777 | 0.71 | IKBKB (0.38) | GRM5MAOBMAOACCNA2CDK2 | |
| SCHEMBL13439675 | 0.71 | IKBKB (0.61) | GRM5MAOBCCNA2CDK2CDK5 | |
| SCHEMBL9958935 | 0.71 | GRM5 (0.70) | GRM5MAOBMAOASYKCCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013092460-A1 | CYCLIC BISOXIME MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-06-27 | — | — | WO | disclosed |
| WO-2013092460-A1 | CYCLIC BISOXIME MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-06-27 | — | — | WO | disclosed |