Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MLNR | O43193 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4690758 | 0.99 | KMT2A (0.61) | KMT2AGAAMEN1KDM4EPOLB | |
| SCHEMBL4689267 | 0.88 | KMT2A (0.79) | KMT2AGAAMEN1KDM4EPOLB | |
| SCHEMBL15061309 | 0.87 | KMT2A (0.64) | KMT2AGAAMEN1KDM4EPOLB | |
| SCHEMBL4692845 | 0.87 | KMT2A (0.64) | KMT2AGAAMEN1KDM4EPOLB | |
| SCHEMBL15061215 | 0.87 | KMT2A (0.55) | KMT2AGAAMEN1KDM4EPOLB | |
| Hydrochloric Acid SCHEMBL4746838 | 0.86 | KMT2A (0.63) | KMT2AGAAMEN1KDM4EPOLB | |
| Hydrochloric Acid SCHEMBL4686782 | 0.86 | KMT2A (0.54) | KMT2AGAAMEN1KDM4EPOLB | |
| SCHEMBL4686780 | 0.84 | KMT2A (0.51) | KMT2AGAAMEN1KDM4EALOX12 | |
| SCHEMBL4686785 | 0.84 | KMT2A (0.51) | KMT2AGAAMEN1KDM4EALOX12 | |
| SCHEMBL15061250 | 0.83 | KMT2A (0.41) | KMT2AGAAMEN1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476275-B2 | N-[piperazinyl hetaryl]arylsufonamide compounds with affinity for the dopamine D3 receptor | ABBOTT GMBH & CO. KG (DE) | 2013-07-02 | — | — | US | claimed |