Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2493416 | 0.67 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1 | |
| SCHEMBL13890096 | 0.61 | SMN1; SMN2 (0.45) | SMN1; SMN2 | |
| SCHEMBL7297395 | 0.61 | SMN1; SMN2 (0.41) | SMN1; SMN2 | |
| SCHEMBL21531656 | 0.61 | SMN1; SMN2 (0.37) | SMN1; SMN2 | |
| SCHEMBL11530404 | 0.61 | SMN1; SMN2 (0.37) | SMN1; SMN2NPC1 | |
| SCHEMBL13607108 | 0.58 | ERN1 (0.50) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL9455125 | 0.58 | GAA (0.38) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL29870960 | 0.58 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL11761527 | 0.58 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL24420566 | 0.55 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8470990-B2 | Ribosome structure and protein synthesis inhibitors | RIB-X PHARMACEUTICALS, INC. (US) | 2013-06-25 | — | — | US | disclosed |