Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 20/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1936756 | 0.93 | BRAF (0.45) | BRAF | |
| SCHEMBL2670744 | 0.91 | BRAF (0.50) | BRAF | |
| SCHEMBL1935520 | 0.90 | BRAF (0.56) | BRAF | |
| SCHEMBL1936946 | 0.90 | BRAF (0.53) | BRAF | |
| SCHEMBL1935710 | 0.89 | MAPK14 (0.54) | BRAF | |
| SCHEMBL1936671 | 0.89 | GSK3A (0.45) | BRAF | |
| SCHEMBL1936478 | 0.88 | BRAF (0.52) | BRAF | |
| SCHEMBL1937040 | 0.88 | BRAF (0.58) | BRAF | |
| SCHEMBL15062908 | 0.88 | BRAF (0.49) | BRAF | |
| SCHEMBL1935735 | 0.88 | BRAF (0.47) | BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331506-B1 | NOVEL BENZAMIDES, PRODUCTION THEREOF, AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM INT (DE) | 2013-07-03 | — | — | EP | disclosed |