SCHEMBL15067003

SCHEMBL15067003

COC(=O)c1ccccc1C(=O)OO

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.63
LMNA P02545 2/20 0.63
ALDH1A1 P00352 3/20 0.61
HSD17B10 Q99714 2/20 0.61
CFTR P13569 1/20 0.61
SLC6A3 Q01959 3/20 0.59
SLC6A4 P31645 2/20 0.59
KDM4E B2RXH2 3/20 0.59
POLB P06746 1/20 0.59
ATM Q13315 1/20 0.59
MAPT P10636 2/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA5A P35218 1/20 0.53
CA9 Q16790 1/20 0.53
ALOX15 P16050 1/20 0.53
KMT2A Q03164 1/20 0.53
CYP1A2 P05177 2/20 0.53
CYP2D6 P10635 1/20 0.53
CYP2C19 P33261 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethyl Phthalate SCHEMBL790124 0.91 TSHR (0.74) TSHRLMNAALDH1A1HSD17B10CFTR
Dimethyl Phthalate SCHEMBL29500970 0.91 TSHR (0.74) TSHRLMNAALDH1A1HSD17B10CFTR
Dimethyl Phthalate SCHEMBL34630 0.91 TSHR (0.74) TSHRLMNAALDH1A1HSD17B10CFTR
Dimethyl Phthalate SCHEMBL29669976 0.91 TSHR (0.74) TSHRLMNAALDH1A1HSD17B10CFTR
Dimethyl Phthalate SCHEMBL28376050 0.88 TSHR (0.71) TSHRLMNAALDH1A1HSD17B10CFTR
Dimethyl Phthalate SCHEMBL27349529 0.88 TSHR (0.71) TSHRLMNAALDH1A1HSD17B10CFTR
Dimethyl Phthalate SCHEMBL28288614 0.88 TSHR (0.71) TSHRLMNAALDH1A1HSD17B10CFTR
Dimethyl Phthalate SCHEMBL10602130 0.88 TSHR (0.71) TSHRLMNAALDH1A1HSD17B10CFTR
Dimethyl Phthalate SCHEMBL30278536 0.88 TSHR (0.71) TSHRLMNAALDH1A1HSD17B10CFTR
Dimethyl Phthalate SCHEMBL28064028 0.88 TSHR (0.71) TSHRLMNAALDH1A1HSD17B10CFTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013100811-A1 PROCESS FOR OBTAINING 16α,17α-CYCLOHEXANO-5α,6α-EPOXYPREGN-3β-OL-20-ONE ACETATE LIMITED LIABILITY COMPANY IZVARINO PHARMA (RU) 2013-07-04 WO claimed
WO-2013100811-A1 PROCESS FOR OBTAINING 16α,17α-CYCLOHEXANO-5α,6α-EPOXYPREGN-3β-OL-20-ONE ACETATE LIMITED LIABILITY COMPANY IZVARINO PHARMA (RU) 2013-07-04 WO disclosed
WO-2013100811-A1 PROCESS FOR OBTAINING 16α,17α-CYCLOHEXANO-5α,6α-EPOXYPREGN-3β-OL-20-ONE ACETATE LIMITED LIABILITY COMPANY IZVARINO PHARMA (RU) 2013-07-04 WO disclosed