Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.54 |
| ▸ | CCR5 | P51681 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.37 |
| ▸ | CCR8 | P51685 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31186679 | 0.86 | CCR1 (0.54) | CCR1CCR5RAB9AMETAP2CYP1A2 | |
| SCHEMBL11804743 | 0.86 | CCR1 (0.54) | CCR1CCR5RAB9AMETAP2CYP1A2 | |
| SCHEMBL12404220 | 0.80 | CCR1 (0.52) | CCR1CCR5RAB9AMETAP2CYP1A2 | |
| SCHEMBL15067245 | 0.78 | CCR1 (0.50) | CCR1CCR5RAB9AMETAP2CYP1A2 | |
| SCHEMBL15067776 | 0.78 | CCR1 (0.50) | CCR1CCR5RAB9AMETAP2CYP1A2 | |
| SCHEMBL11561888 | 0.78 | KDM4E (0.52) | CCR1CCR5RAB9AMETAP2CYP1A2 | |
| SCHEMBL29324261 | 0.77 | CCR1 (0.48) | CCR1CCR5RAB9AMETAP2CYP1A2 | |
| SCHEMBL28529190 | 0.75 | NFKBIA (0.50) | CCR1CCR5RAB9ACYP1A2LMNA | |
| SCHEMBL28910024 | 0.74 | CCR1 (0.45) | CCR1CCR5RAB9AMETAP2CYP1A2 | |
| SCHEMBL27440133 | 0.73 | CCR1 (0.54) | CCR1CCR5RAB9AMETAP2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2771323-B1 | A BIS-QUINALDINE COMPOUND AND A PROCESS FOR PREPARING THE SAME | GHARDA KEKI HORMUSJI (IN) | 2017-08-30 | — | — | EP | disclosed |
| US-9062000-B2 | Bis-quinaldine compound and a process for preparing the same | Gharda Medical and Advanced Technologies Foundation (IN) | 2015-06-23 | — | — | US | disclosed |
| US-20140296529-A1 | BIS-QUINALDINE COMPOUND AND A PROCESS FOR PREPARING THE SAME | Gharda Medical and Advanced Technologies Foundation (IN) | 2014-10-02 | — | — | US | disclosed |
| EP-2771323-A2 | A BIS-QUINALDINE COMPOUND AND A PROCESS FOR PREPARING THE SAME | Gharda, Keki Hormusji (IN) | 2014-09-03 | — | — | EP | disclosed |
| WO-2013098837-A2 | A BIS-QUINALDINE COMPOUND AND A PROCESS FOR PREPARING THE SAME | GHARDA KEKI HORMUSJI (IN) | 2013-07-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296529-A1 | BIS-QUINALDINE COMPOUND AND A PROCESS FOR PREPARING THE SAME | NQO1, NQO2, SQLE | CCR1 3648/4885CCR5 2438/4885RAB9A 148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.