Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.72 |
| ▸ | MAPT | P10636 | 4/20 | 0.72 |
| ▸ | PKM | P14618 | 2/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.72 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.72 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.69 |
| ▸ | SERPINE1 | P05121 | 4/20 | 0.68 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.61 |
| ▸ | DHODH | Q02127 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | GFER | P55789 | 1/20 | 0.60 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.58 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.56 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.56 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12700346 | 0.88 | HSD17B10 (0.61) | MEN1KMT2AMAPTPKMTDP1 | |
| SCHEMBL21953116 | 0.88 | SERPINE1 (0.76) | MEN1KMT2AMAPTPKMTDP1 | |
| SCHEMBL30267981 | 0.88 | SERPINE1 (0.76) | MEN1KMT2AMAPTPKMTDP1 | |
| SCHEMBL6096421 | 0.86 | MEN1 (0.74) | MEN1KMT2AMAPTPKMTDP1 | |
| SCHEMBL1954779 | 0.86 | MEN1 (0.72) | MEN1KMT2AMAPTPKMTDP1 | |
| SCHEMBL14075414 | 0.85 | MEN1 (0.70) | MEN1KMT2AMAPTPKMTDP1 | |
| SCHEMBL6109346 | 0.84 | SERPINE1 (0.77) | MEN1KMT2AMAPTTDP1SERPINE1 | |
| SCHEMBL1056451 | 0.84 | KMT2A (1.00) | MEN1KMT2AMAPTPKMTDP1 | |
| SCHEMBL11834604 | 0.83 | MEN1 (0.85) | MEN1KMT2AMAPTPKMTDP1 | |
| SCHEMBL6351321 | 0.83 | SERPINE1 (0.89) | MEN1KMT2AMAPTPKMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2797930-B1 | FGF RECEPTOR (FGFR) AGONIST DIMERIC COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2016-07-13 | — | — | EP | disclosed |
| US-9206177-B2 | Substituted dimeric quinazoline-2,4-diones as FGF receptor agonists | SANOFI (FR) | 2015-12-08 | — | — | US | disclosed |
| US-9206177-B2 | Substituted dimeric quinazoline-2,4-diones as FGF receptor agonists | SANOFI (FR) | 2015-12-08 | — | — | US | disclosed |
| US-20140378483-A1 | FGF Receptor (FGFR) Agonist Dimeric Compounds, Process for the Preparation Thereof and Therapeutic Use Thereof | SANOFI (FR) | 2014-12-25 | — | — | US | disclosed |
| US-20140378483-A1 | FGF Receptor (FGFR) Agonist Dimeric Compounds, Process for the Preparation Thereof and Therapeutic Use Thereof | SANOFI (FR) | 2014-12-25 | — | — | US | disclosed |
| EP-2797930-A1 | FGF RECEPTOR (FGFR) AGONIST DIMERIC COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2014-11-05 | — | — | EP | disclosed |
| WO-2013098763-A1 | FGF RECEPTOR (FGFR) AGONIST DIMERIC COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2013-07-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140378483-A1 | FGF Receptor (FGFR) Agonist Dimeric Compounds, Process for the Preparation Thereof and Therapeutic Use Thereof | FGFR1, FGFR2, FGF2 | MEN1 1168/4885KMT2A 2004/4885MAPT 2655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.