Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 18/20 | 0.79 |
| ▸ | PPARD | Q03181 | 17/20 | 0.79 |
| ▸ | PPARG | P37231 | 12/20 | 0.79 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15068185 | 0.90 | PPARA (0.69) | PPARAPPARDPPARGLMNACYP2C9 | |
| SCHEMBL16243352 | 0.89 | PPARA (0.64) | PPARAPPARDPPARGTSHR | |
| SCHEMBL15068158 | 0.89 | PPARA (0.68) | PPARAPPARDPPARGLMNACYP2C9 | |
| SCHEMBL15067511 | 0.89 | PPARD (1.00) | PPARAPPARDPPARG | |
| SCHEMBL15067582 | 0.88 | PPARA (0.67) | PPARAPPARDPPARGLMNACYP2C9 | |
| SCHEMBL16243154 | 0.83 | PPARA (0.84) | PPARAPPARDPPARGLMNACYP2C9 | |
| SCHEMBL16243199 | 0.81 | PPARA (0.57) | PPARAPPARDPPARGTSHR | |
| SCHEMBL16242791 | 0.80 | PPARA (0.56) | PPARAPPARDPPARGTSHR | |
| SCHEMBL16243217 | 0.79 | PPARA (0.56) | PPARAPPARDPPARGTSHR | |
| SCHEMBL15067357 | 0.79 | PPARD (1.00) | PPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115073-B2 | 1,3-diphenylpropane derivatives, preparations and uses thereof | GENFIT (FR) | 2015-08-25 | — | — | US | claimed |
| EP-2811992-A1 | 1,3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES THEREOF | Genfit (FR) | 2014-12-17 | — | — | EP | claimed |
| US-20140350112-A1 | 1,3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES THEREOF | GENFIT (FR) | 2014-11-27 | — | — | US | claimed |
| WO-2013098374-A1 | 1,3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES THEREOF | GENFIT (FR) | 2013-07-04 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140350112-A1 | 1,3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES THEREOF | PPARD, PPARA, PPARG | PPARA 2/4885PPARD 1/4885PPARG 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.