SCHEMBL15068233

SCHEMBL15068233

CC(C)SSC(C(=O)O)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.45
SRC P12931 1/20 0.45
LMNA P02545 3/20 0.43
MAPK1 P28482 1/20 0.43
PTGS2 P35354 1/20 0.41
ALDH1A1 P00352 3/20 0.41
PKM P14618 2/20 0.41
APAF1 O14727 1/20 0.41
KDM4E B2RXH2 1/20 0.41
GAA P10253 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
AURKB Q96GD4 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4828917 0.89 SRC (0.54) CYP2D6SRCLMNAMAPK1ALDH1A1
SCHEMBL21961154 0.82 CYP2D6 (0.46) CYP2D6SRCLMNAMAPK1PTGS2
SCHEMBL21687919 0.77 SRC (0.50) CYP2D6SRCLMNAMAPK1ALDH1A1
SCHEMBL4740644 0.77 SRC (0.50) CYP2D6SRCLMNAMAPK1ALDH1A1
SCHEMBL21687922 0.77 SRC (0.50) CYP2D6SRCLMNAMAPK1ALDH1A1
SCHEMBL14506219 0.76 SRC (0.54) CYP2D6SRCLMNAMAPK1ALDH1A1
SCHEMBL2119361 0.73 CYP2D6 (0.46) CYP2D6SRCLMNAMAPK1PTGS2
SCHEMBL7303575 0.73 CYP2D6 (0.46) CYP2D6SRCLMNAMAPK1PTGS2
SCHEMBL28787282 0.72 EPHX1 (0.53) CYP2D6SRCLMNAMAPK1
SCHEMBL3060024 0.72 SRC (0.50) CYP2D6SRCLMNAMAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2798001-A1 METHOD FOR PRODUCING PURIFIED NITRILE RUBBERS LANXESS Deutschland GmbH (DE) 2014-11-05 EP disclosed
WO-2013098073-A1 METHOD FOR PRODUCING PURIFIED NITRILE RUBBERS LANXESS DEUTSCHLAND GMBH (DE) 2013-07-04 WO disclosed