Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.49 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.32 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.31 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | HTR5A | P47898 | 1/20 | 0.31 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.31 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15086180 | 0.91 | MIF (0.59) | MIFKHKCHRNB2CHRNA4NPC1 | |
| SCHEMBL15086189 | 0.89 | MIF (0.61) | MIFPDE7APDE4DPDE7BKHK | |
| SCHEMBL15065976 | 0.85 | MIF (0.66) | MIFKHKSLC16A3HTR3EHTR3B | |
| SCHEMBL16669582 | 0.77 | MIF (0.45) | MIFPDE7APDE4DPDE7BKHK | |
| SCHEMBL16669743 | 0.77 | MIF (0.60) | MIFSLC16A3HTR3AALKHTR6 | |
| SCHEMBL15067288 | 0.76 | MIF (0.64) | MIFSLC16A3HTR3AALKHTR6 | |
| SCHEMBL16669565 | 0.76 | MIF (0.61) | MIFKHKSLC16A3ALKNPC1 | |
| SCHEMBL21291692 | 0.74 | MIF (0.62) | MIFKHKSLC16A3ALKNPC1 | |
| SCHEMBL21291693 | 0.74 | MIF (0.62) | MIFKHKSLC16A3ALKNPC1 | |
| SCHEMBL15068994 | 0.74 | MIF (0.62) | MIFKHKSLC16A3ALKNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2797592-A1 | COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY | PTC Therapeutics, Inc. (US) | 2014-11-05 | — | — | EP | claimed |
| WO-2013101974-A1 | COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY | PTC THERAPEUTICS, INC. (US) | 2013-07-04 | — | — | WO | claimed |