Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15069451 | 0.85 | BRD4 (1.00) | BRD4 | |
| SCHEMBL15069438 | 0.84 | BRD4 (0.74) | BRD4 | |
| SCHEMBL15069201 | 0.83 | BRD4 (0.86) | BRD4 | |
| SCHEMBL15067827 | 0.83 | BRD4 (1.00) | BRD4 | |
| SCHEMBL15770881 | 0.83 | BRD4 (0.73) | BRD4 | |
| SCHEMBL28386060 | 0.83 | BRD4 (1.00) | BRD4 | |
| SCHEMBL30517706 | 0.83 | BRD4 (1.00) | BRD4 | |
| SCHEMBL15069231 | 0.82 | BRD4 (1.00) | BRD4 | |
| SCHEMBL15068232 | 0.80 | BRD4 (1.00) | BRD4 | |
| SCHEMBL29745786 | 0.80 | BRD4 (1.00) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2797918-A1 | BROMODOMAIN INHIBITORS | AbbVie Inc. (US) | 2014-11-05 | — | — | EP | claimed |
| WO-2013097601-A1 | BROMODOMAIN INHIBITORS | ABBVIE INC. (US) | 2013-07-04 | — | — | WO | claimed |
| EP-2797918-B1 | BROMODOMAIN INHIBITORS | ABBVIE INC (US) | 2017-11-29 | — | — | EP | disclosed |
| EP-2797918-A1 | BROMODOMAIN INHIBITORS | AbbVie Inc. (US) | 2014-11-05 | — | — | EP | disclosed |
| WO-2013097601-A1 | BROMODOMAIN INHIBITORS | ABBVIE INC. (US) | 2013-07-04 | — | — | WO | disclosed |