SCHEMBL15069776

SCHEMBL15069776

COC[CH]Cc1ccc(Cl)cc1Cl

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 6/20 0.49
IDO1 P14902 5/20 0.46
MAPK1 P28482 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
ALDH1A1 P00352 3/20 0.42
MAPT P10636 2/20 0.41
POLB P06746 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.39
NPC1 O15118 1/20 0.39
LMNA P02545 1/20 0.39
RAB9A P51151 1/20 0.39
NR4A2 P43354 1/20 0.39
PYCR1 P32322 1/20 0.38
HDAC8 Q9BY41 1/20 0.37
HPGD P15428 1/20 0.37
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4995355 0.76 IDO1 (0.50) HTTIDO1MAPK1CYP1A2CYP3A4
SCHEMBL4997086 0.76 IDO1 (0.50) HTTIDO1MAPK1CYP1A2CYP3A4
SCHEMBL5006071 0.75 IDO1 (0.46) HTTIDO1MAPK1CYP1A2CYP3A4
SCHEMBL1989192 0.75 IDO1 (0.64) HTTIDO1MAPK1CYP1A2CYP3A4
SCHEMBL6033569 0.75 IDO1 (0.54) HTTIDO1MAPK1CYP1A2CYP3A4
SCHEMBL16770980 0.72 HTT (0.62) HTTIDO1MAPK1CYP1A2CYP3A4
SCHEMBL248225 0.72 IDO1 (0.50) HTTIDO1MAPK1CYP1A2CYP3A4
SCHEMBL8091192 0.72 IDO1 (0.50) HTTIDO1MAPK1CYP1A2CYP3A4
SCHEMBL7465808 0.71 IDO1 (0.42) HTTIDO1MAPK1CYP1A2CYP3A4
SCHEMBL895205 0.71 IDO1 (0.54) HTTIDO1MAPK1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2797881-A1 Phenyl alkyl carbamate derivative compound and pharmaceutical composition containing the same Bio-Pharm Solutions Co., Ltd. (KR) 2014-11-05 EP disclosed
WO-2013100566-A1 Phenyl alkyl carbamate derivative compound and pharmaceutical composition containing the same BIO-PHARM SOLUTIONS CO., LTD. (KR) 2013-07-04 WO disclosed