SCHEMBL15070944

SCHEMBL15070944

CCCCC/C=C\C/C=C\CCCCCCCC1OC(CCCC)OC1CCCCCCC/C=C\C/C=C\CCCCC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.46
TRPV1 Q8NER1 1/20 0.44
ALOX5 P09917 1/20 0.44
ALDH1A1 P00352 4/20 0.44
KDM4E B2RXH2 3/20 0.44
F7 P08709 3/20 0.44
F3 P13726 3/20 0.44
PPARG P37231 2/20 0.44
PPARD Q03181 2/20 0.44
PPARA Q07869 2/20 0.44
FABP3 P05413 2/20 0.44
DUSP3 P51452 1/20 0.44
PTPN7 P35236 1/20 0.44
FFAR1 O14842 1/20 0.44
LMNA P02545 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP19A1 P11511 1/20 0.44
FABP4 P15090 1/20 0.44
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12297074 0.91 KDM4E (0.43) MAPTTRPV1ALOX5ALDH1A1KDM4E
SCHEMBL19033138 0.88 MAPT (0.40) MAPTTRPV1ALOX5ALDH1A1KDM4E
SCHEMBL2621202 0.88 CNR1 (0.41) MAPTTRPV1ALOX5ALDH1A1KDM4E
SCHEMBL15150553 0.87 KDM4E (0.40) MAPTALOX5KDM4ESOAT1
SCHEMBL15074655 0.87 MAPT (0.42) MAPTTRPV1ALOX5ALDH1A1KDM4E
SCHEMBL31264379 0.86 CNR1 (0.42) MAPTTRPV1ALOX5ALDH1A1KDM4E
SCHEMBL2621200 0.86 CNR1 (0.42) MAPTTRPV1ALOX5ALDH1A1KDM4E
SCHEMBL31264377 0.86 CNR1 (0.42) MAPTTRPV1ALOX5ALDH1A1KDM4E
SCHEMBL31264386 0.86 CNR1 (0.42) MAPTTRPV1ALOX5ALDH1A1KDM4E
SCHEMBL19525649 0.85 CNR1 (0.39) MAPTTRPV1ALOX5ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9687550-B2 Compositions for nucleic acid delivery ARBUTUS BIOPHARMA CORPORATION (CA) 2017-06-27 US disclosed
US-20130196410-A1 COMPOSITIONS AND METHODS FOR MODIFYING THE GLYCOSYLATION PATTERN OF A POLYPEPTIDE ALNYLAM PHARMACEUTICALS, INC (US) 2013-08-01 US disclosed
US-20130164851-A1 GENE AMPLIFICATION AND TRANSFECTION METHODS AND REAGENTS RELATED THERETO ALNYLAM PHARMACEUTICALS, INC. (US) 2013-06-27 US disclosed