Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 18/20 | 0.67 |
| ▸ | PDE6C | P51160 | 4/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.63 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | PDE1A | P54750 | 2/20 | 0.63 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.63 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.62 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | PDE2A | O00408 | 1/20 | 0.60 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.60 |
| ▸ | ABCC5 | O15440 | 1/20 | 0.60 |
| ▸ | PDE6D | O43924 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19181253 | 0.90 | PDE5A (0.75) | PDE5APDE6CHDAC6HDAC1PDE3A | |
| SCHEMBL681658 | 0.88 | PDE5A (0.71) | PDE5APDE6CHDAC6HDAC1PDE3A | |
| SCHEMBL19181375 | 0.88 | PDE5A (0.72) | PDE5APDE6CHDAC6HDAC1PDE3A | |
| SCHEMBL17390180 | 0.87 | PDE5A (0.72) | PDE5APDE6CHDAC6HDAC1PDE3A | |
| SCHEMBL16003778 | 0.87 | PDE5A (0.89) | PDE5APDE6CHDAC6HDAC1PDE3A | |
| SCHEMBL25013467 | 0.86 | PDE5A (0.77) | PDE5APDE6CHDAC6HDAC1PDE3A | |
| SCHEMBL18715171 | 0.85 | PDE5A (0.75) | PDE5APDE6CHDAC6HDAC1PDE3A | |
| SCHEMBL15423769 | 0.85 | PDE5A (0.68) | PDE5APDE6CHDAC6HDAC1PDE3A | |
| SCHEMBL25925219 | 0.85 | PDE5A (0.62) | PDE5APDE6CHDAC6HDAC1PDE3A | |
| SCHEMBL17390127 | 0.84 | PDE5A (0.75) | PDE5APDE6CHDAC6HDAC1PDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663439-B2 | Aildenafil citrate crystal form O, preparation method and use thereof | HONG KONG GOLDEN WISDOM MEDICAL PRODUCTION LIMITED (HK) | 2017-05-30 | — | — | US | disclosed |
| US-20130165448-A1 | AILDENAFIL CITRATE CRYSTAL FORM O, PREPARATION METHOD AND USE THEREOF | HONG KONG GOLDEN WISDOM MEDICAL PRODUCTION LIMITED (HK) | 2013-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165448-A1 | AILDENAFIL CITRATE CRYSTAL FORM O, PREPARATION METHOD AND USE THEREOF | PDE5A, PDE3A, PDE3B | PDE5A 1/4885PDE6C 91/4885HDAC6 1167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.