SCHEMBL1507318

SCHEMBL1507318

[Li]C1=Cc2ccccc2C1C(C)C

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.33
PRCP P42785 1/20 0.32
BRD4 O60885 1/20 0.30
CCL2 P13500 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27774613 0.77 HTR2A (0.34) HTR2APRCP
SCHEMBL29069610 0.75 HTR2A (0.37) HTR2APRCP
SCHEMBL28417072 0.75 HTR2A (0.33) HTR2APRCP
SCHEMBL11129932 0.75 HTR2A (0.33) HTR2APRCP
SCHEMBL26606712 0.75 HTR2A (0.33) HTR2APRCP
SCHEMBL574074 0.75 HTR2A (0.33) HTR2APRCP
SCHEMBL29842098 0.74 BRD4 (0.43) HTR2ABRD4CCL2
SCHEMBL7827111 0.74 BRD4 (0.43) HTR2ABRD4CCL2
Bromide SCHEMBL28806999 0.73 HTR2A (0.32) HTR2APRCP
Iodide SCHEMBL28810157 0.73 HTR2A (0.32) HTR2APRCP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103601831-B The oligopolymer based on propylene of high-vinyl end-blocking EXXON CHEMICAL PATENTS INC. (US) 2016-03-16 CN disclosed
US-8779067-B2 High vinyl terminated propylene based oligomers EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-07-15 US disclosed
US-8735502-B2 Functionalized high vinyl terminated propylene based oligomers EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-05-27 US disclosed
US-8653209-B2 High vinyl terminated propylene based oligomers EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-02-18 US disclosed
US-20130137830-A1 Functionalized High Vinyl Terminated Propylene Based Oligomers EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-05-30 US disclosed
EP-2288630-B1 HIGH VINYL TERMINATED PROPYLENE BASED OLIGOMERS EXXONMOBIL CHEM PATENTS INC (US) 2013-05-08 EP disclosed
US-8399725-B2 Functionalized high vinyl terminated propylene based oligomers EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-03-19 US disclosed
US-20130066103-A1 High Vinyl Terminated Propylene Based Oligomers EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-03-14 US disclosed
US-20130059992-A1 High Vinyl Terminated Propylene Based Oligomers EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-03-07 US disclosed
US-8372930-B2 High vinyl terminated propylene based oligomers EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-02-12 US disclosed
EP-2300503-A2 FUNCTIONALIZED HIGH VINYL TERMINATED PROPYLENE BASED OLIGOMERS ExxonMobil Chemical Patents Inc. (US) 2011-03-30 EP disclosed
EP-2288630-A2 HIGH VINYL TERMINATED PROPYLENE BASED OLIGOMERS ExxonMobil Chemical Patents Inc. (US) 2011-03-02 EP disclosed
US-20090318644-A1 High Vinyl Terminated Propylene Based Oligomers EXXONMOBIL CHEMICAL PATENTS INC. 2009-12-24 US disclosed
US-20090318646-A1 Functionalized High Vinyl Terminated Propylene Based Oligomers EXXONMOBIL CHEMICAL PATENTS INC. 2009-12-24 US disclosed
WO-2009155471-A2 HIGH VINYL TERMINATED PROPYLENE BASED OLIGOMERS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2009-12-23 WO disclosed
WO-2009155472-A2 FUNCTIONALIZED HIGH VINYL TERMINATED PROPYLENE BASED OLIGOMERS EXXONMOBILE CHEMICAL PATENTS INC. (US) 2009-12-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130059992-A1 High Vinyl Terminated Propylene Based Oligomers MAX, AP3M1, AP1M1 HTR2A 3090/4885PRCP 4411/4885BRD4 3358/4885
US-20130066103-A1 High Vinyl Terminated Propylene Based Oligomers MAX, AP3M1, AP1M1 HTR2A 3090/4885PRCP 4411/4885BRD4 3358/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.