SCHEMBL15076320

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15276933	0.94	SIRT2 (0.56)	KMT2AMEN1SIRT2CASP1HTT
	SCHEMBL15276930	0.94	KMT2A (0.61)	KMT2AMEN1SIRT2CASP1HTT
	SCHEMBL15276928	0.92	KMT2A (0.57)	KMT2AMEN1SIRT2CASP1HTT
	SCHEMBL15076347	0.91	KMT2A (0.67)	KMT2AMEN1SIRT2CASP1HTT
	SCHEMBL15276979	0.90	KMT2A (0.54)	KMT2AMEN1SIRT2CASP1HTT
	SCHEMBL15076555	0.89	KMT2A (0.55)	KMT2AMEN1SIRT2CASP1HTT
	SCHEMBL15076655	0.89	KMT2A (0.59)	KMT2AMEN1SIRT2CASP1HTT
	SCHEMBL15076327	0.89	HTR2B (0.59)	KMT2AMEN1CASP1HTTHSD17B10
	SCHEMBL19157265	0.87	KMT2A (0.62)	KMT2AMEN1SIRT2CASP1HTT
	SCHEMBL15280079	0.87	KMT2A (0.55)	KMT2AMEN1SIRT2CASP1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.