SCHEMBL15076589

SCHEMBL15076589

NNc1cc(F)c(F)cc1F

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
CA9 Q16790 2/20 0.43
CA12 O43570 1/20 0.34
ALDH1A1 P00352 1/20 0.30
POLB P06746 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3844562 0.97 CA1 (0.42) CA1CA2CA9CA12ALDH1A1
Bromide SCHEMBL20985008 0.97 CA1 (0.42) CA1CA2CA9CA12
Phosphoric Acid SCHEMBL20984431 0.86 CA1 (0.40) CA1CA2CA9CA12
Oxalic Acid SCHEMBL20985013 0.86 CA1 (0.40) CA1CA2CA9CA12ALDH1A1
Sulfuric Acid SCHEMBL20984727 0.86 CA1 (0.48) CA1CA2CA9CA12
Nitric Acid SCHEMBL20984387 0.82 CA1 (0.42) CA1CA2CA9CA12ALDH1A1
SCHEMBL24190192 0.79 CA1 (0.38) CA1CA2CA9ALDH1A1TDP1
SCHEMBL3234702 0.79 CA1 (0.42) CA1CA2CA9
SCHEMBL13496828 0.79 CA1 (0.38) CA1CA2CA9
SCHEMBL22965640 0.78 PIM1 (0.38) CA1CA2CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107663161-A A kind of continuous stream synthesis technique of phenylhydrazine salt and substituted benzene hydrazonium salt 上海惠和化德生物科技有限公司 2018-02-06 CN disclosed
WO-2013096744-A1 HEPATITIS B ANTIVIRAL AGENTS NOVIRA THERAPEUTICS, INC. (US) 2013-06-27 WO disclosed
CN-101573339-A Novel cannabinoid receptor ligands, pharmaceutical compositions containing them, and processes for their preparation GLENMARK PHARMACEUTICALS SA (CH) 2009-11-04 CN disclosed