Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | BRD2 | P25440 | 1/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.49 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LOX | P28300 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15276970 | 1.00 | MEN1 (0.59) | MEN1KMT2AHTR2BTP53MAPT | |
| SCHEMBL15276971 | 1.00 | MEN1 (0.59) | MEN1KMT2AHTR2BTP53MAPT | |
| SCHEMBL15076667 | 0.92 | MEN1 (0.52) | MEN1KMT2ATP53MAPTBRD4 | |
| SCHEMBL15076307 | 0.92 | MAPT (0.55) | MEN1KMT2AHTR2BTP53MAPT | |
| SCHEMBL15276929 | 0.92 | MEN1 (0.49) | MEN1KMT2AHTR2BTP53MAPT | |
| SCHEMBL15076654 | 0.92 | MAPT (0.55) | MEN1KMT2ATP53MAPTBRD4 | |
| SCHEMBL15076747 | 0.91 | MAPT (0.50) | MEN1KMT2AHTR2BTP53MAPT | |
| SCHEMBL15076475 | 0.91 | MEN1 (0.49) | MEN1KMT2AHTR2BTP53MAPT | |
| SCHEMBL15280077 | 0.90 | BRD4 (0.54) | MEN1KMT2AHTR2BTP53MAPT | |
| SCHEMBL15280072 | 0.89 | MEN1 (0.47) | MEN1KMT2AHTR2BTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312160-B1 | HEPATITIS B ANTIVIRAL AGENTS | NOVIRA THERAPEUTICS INC (US) | 2020-03-18 | — | — | EP | disclosed |
| EP-3312160-A1 | HEPATITIS B ANTIVIRAL AGENTS | Novira Therapeutics Inc. (US) | 2018-04-25 | — | — | EP | disclosed |
| WO-2013096744-A1 | HEPATITIS B ANTIVIRAL AGENTS | NOVIRA THERAPEUTICS, INC. (US) | 2013-06-27 | — | — | WO | disclosed |