Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MPI | P34949 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 2/20 | 0.46 |
| ▸ | BTK | Q06187 | 2/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL14120084 | 0.98 | HTT (0.60) | TAAR1HTTRXFP1ATMNPSR1 | |
| SCHEMBL8217518 | 0.87 | TAAR1 (0.52) | TAAR1HTTRXFP1NPSR1MEN1 | |
| SCHEMBL8223783 | 0.85 | TAAR1 (0.43) | TAAR1HTTRXFP1ATMNPSR1 | |
| SCHEMBL3935647 | 0.80 | HTT (0.57) | TAAR1HTTRXFP1ATMNPSR1 | |
| SCHEMBL19157555 | 0.80 | HTT (0.57) | TAAR1HTTRXFP1ATMNPSR1 | |
| SCHEMBL6701678 | 0.78 | RXFP1 (0.72) | TAAR1HTTRXFP1ATMNPSR1 | |
| SCHEMBL2221552 | 0.77 | MEN1 (0.67) | TAAR1HTTRXFP1ATMNPSR1 | |
| SCHEMBL113076 | 0.77 | TAAR1 (0.73) | TAAR1HTTRXFP1ATMNPSR1 | |
| SCHEMBL8225441 | 0.76 | CD38 (0.39) | TAAR1HTTRXFP1ATMNPSR1 | |
| SCHEMBL8065706 | 0.76 | HTT (0.62) | TAAR1HTTRXFP1ATMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312160-B1 | HEPATITIS B ANTIVIRAL AGENTS | NOVIRA THERAPEUTICS INC (US) | 2020-03-18 | — | — | EP | disclosed |
| WO-2013096744-A1 | HEPATITIS B ANTIVIRAL AGENTS | NOVIRA THERAPEUTICS, INC. (US) | 2013-06-27 | — | — | WO | disclosed |