Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 20/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16222240 | 1.00 | FLT3 (0.83) | FLT3 | |
| SCHEMBL15079467 | 1.00 | FLT3 (0.83) | FLT3 | |
| SCHEMBL15079468 | 0.94 | FLT3 (0.81) | FLT3 | |
| SCHEMBL16222238 | 0.94 | FLT3 (0.81) | FLT3 | |
| SCHEMBL15079479 | 0.94 | FLT3 (0.81) | FLT3 | |
| SCHEMBL16222239 | 0.91 | FLT3 (0.87) | FLT3 | |
| SCHEMBL15079551 | 0.91 | FLT3 (1.00) | FLT3 | |
| SCHEMBL15079543 | 0.90 | FLT3 (1.00) | FLT3 | |
| SCHEMBL15079522 | 0.90 | FLT3 (0.90) | FLT3 | |
| SCHEMBL15079537 | 0.89 | FLT3 (0.87) | FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2763998-B1 | TRI-HETEROCYCLIC DERIVATIVES, PREPARATION PROCESS AND USES THEREOF | SHANGHAI DE NOVO PHARMATECH CO LTD (CN) | 2016-04-27 | — | — | EP | disclosed |
| WO-2013091502-A1 | TRI-HETEROCYCLIC DERIVATIVES, PREPARATION PROCESS AND USES THEREOF | SHANGHAI DE NOVO PHARMATECH CO LTD. (CN) | 2013-06-27 | — | — | WO | disclosed |