SCHEMBL15079599

SCHEMBL15079599

C[C@H]1CN(CC(O)COc2ccc3c(n2)sc2nc(-c4ccc(NC(=O)Nc5cc(C(C)(C)C)on5)cc4)cn23)[C@@H](C)CO1

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FLT3 P36888 20/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16222243 0.89 FLT3 (0.82) FLT3
SCHEMBL16222241 0.85 FLT3 (0.80) FLT3
SCHEMBL15079606 0.85 FLT3 (0.74) FLT3
SCHEMBL15079598 0.84 FLT3 (0.79) FLT3
SCHEMBL15079592 0.84 FLT3 (0.80) FLT3
SCHEMBL16222253 0.84 FLT3 (0.73) FLT3
SCHEMBL15079600 0.84 FLT3 (0.72) FLT3
SCHEMBL15079615 0.83 FLT3 (0.74) FLT3
SCHEMBL15079579 0.82 FLT3 (0.78) FLT3
SCHEMBL15079576 0.82 FLT3 (0.78) FLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013091502-A1 TRI-HETEROCYCLIC DERIVATIVES, PREPARATION PROCESS AND USES THEREOF SHANGHAI DE NOVO PHARMATECH CO LTD. (CN) 2013-06-27 WO disclosed