SCHEMBL1507994

SCHEMBL1507994

CCO[C@@H](CC)c1ccc(OCc2ccc(Cl)c(Cl)c2)cc1

nearest known ligand 0.74

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 19/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1508447 0.85 FFAR1 (1.00) FFAR1
SCHEMBL1508325 0.85 FFAR1 (1.00) FFAR1
SCHEMBL1537730 0.85 FFAR1 (1.00) FFAR1
SCHEMBL1508523 0.83 FFAR1 (0.80) FFAR1
SCHEMBL24074706 0.79 FFAR1 (0.61) FFAR1
SCHEMBL24071114 0.77 FFAR1 (0.58) FFAR1
SCHEMBL4227054 0.76 FFAR1 (0.55) FFAR1
SCHEMBL1508415 0.75 FFAR1 (0.82) FFAR1
SCHEMBL1508397 0.75 FFAR1 (0.82) FFAR1
SCHEMBL12584867 0.75 MAOB (0.54) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2289868-B1 CARBOXYLIC ACID COMPOUND DAIICHI SANKYO CO LTD (JP) 2014-08-13 EP disclosed
EP-2289868-A1 CARBOXYLIC ACID COMPOUND Daiichi Sankyo Company, Limited (JP) 2011-03-02 EP disclosed