Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | PTGES | O14684 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TSPO | P30536 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | PMM2 | O15305 | 1/20 | 0.36 |
| ▸ | MPI | P34949 | 1/20 | 0.36 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13761981 | 1.00 | KDM4E (0.42) | KDM4EATML3MBTL1PPARGPPARA | |
| SCHEMBL13761982 | 1.00 | KDM4E (0.42) | KDM4EATML3MBTL1PPARGPPARA | |
| SCHEMBL13761720 | 0.97 | KDM4E (0.44) | KDM4EATML3MBTL1PPARGPPARA | |
| SCHEMBL13761729 | 0.97 | KDM4E (0.44) | KDM4EATML3MBTL1PPARGPPARA | |
| SCHEMBL13433164 | 0.97 | KDM4E (0.44) | KDM4EATML3MBTL1PPARGPPARA | |
| SCHEMBL12643567 | 0.97 | KDM4E (0.44) | KDM4EATML3MBTL1PPARGPPARA | |
| SCHEMBL13761721 | 0.97 | KDM4E (0.44) | KDM4EATML3MBTL1PPARGPPARA | |
| SCHEMBL13761722 | 0.97 | KDM4E (0.44) | KDM4EATML3MBTL1PPARGPPARA | |
| SCHEMBL12461805 | 0.97 | KDM4E (0.44) | KDM4EATML3MBTL1PPARGPPARA | |
| SCHEMBL13761730 | 0.97 | KDM4E (0.44) | KDM4EATML3MBTL1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8475935-B2 | — | — | 2013-07-02 | — | — | US | disclosed |
| US-8475935-B2 | — | — | 2013-07-02 | — | — | US | disclosed |