Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 9/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | FAP | Q12884 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1136100 | 0.87 | DPP4 (0.62) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL1136102 | 0.87 | DPP4 (0.62) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL13637938 | 0.87 | DPP4 (0.50) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL1136099 | 0.87 | DPP4 (0.62) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL30406108 | 0.87 | DPP4 (0.62) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL19036875 | 0.81 | DPP4 (0.46) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL13472178 | 0.80 | DPP4 (0.51) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL7919264 | 0.80 | DPP4 (0.41) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL17001389 | 0.78 | DPP4 (0.59) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL16750213 | 0.75 | DPP4 (0.56) | DPP4DPP8DPP9DPP7ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476437-B2 | Process for preparation of (2R)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro [1,2,4]-triazolo[4,3-a]pyrazin-7(8H)-yl]-l-(2,4,5-trifluorophenyl)butan-2-amine and new impurities in preparation thereof | CADILA HEALTHCARE LIMITED (IN) | 2013-07-02 | — | — | US | disclosed |