SCHEMBL15083227

CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)OCc1ccc(N=[N+]=[N-])cc1)C(=O)O[C@H]1[C@@H](O)[C@H](n2cnc3c(N)ncnc32)O[C@@H]1COP(=O)(O)O[C@H]1CC(n2ccc(N)nc2=O)O[C@@H]1COP(=O)(O)O

nearest known ligand 0.44

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	EP300	Q09472	4/20	0.44

▸	KAT5	Q92993	2/20	0.43

▸	CREBBP	Q92793	1/20	0.43

▸	CHAT	P28329	2/20	0.40

▸	NAA50	Q9GZZ1	2/20	0.40

▸	AURKA	O14965	1/20	0.40

▸	KAT2B	Q92831	1/20	0.40

▸	RNASEL	Q05823	7/20	0.40

▸	DOT1L	Q8TEK3	2/20	0.39

▸	TERT	O14746	1/20	0.39

▸	ENPP1	P22413	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL16288580	1.00	EP300 (0.44)	EP300KAT5CREBBPCHATNAA50
SCHEMBL16288572	1.00	EP300 (0.44)	EP300KAT5CREBBPCHATNAA50
SCHEMBL16288568	1.00	EP300 (0.44)	EP300KAT5CREBBPCHATNAA50
SCHEMBL15083477	1.00	EP300 (0.44)	EP300KAT5CREBBPCHATNAA50
SCHEMBL17991821	1.00	EP300 (0.44)	EP300KAT5CREBBPCHATNAA50
SCHEMBL16288584	1.00	EP300 (0.44)	EP300KAT5CREBBPCHATNAA50
SCHEMBL16288576	1.00	EP300 (0.44)	EP300KAT5CREBBPCHATNAA50
SCHEMBL16289028	0.99	EP300 (0.44)	EP300KAT5CREBBPCHATNAA50
SCHEMBL15083204	0.99	EP300 (0.44)	EP300KAT5CREBBPCHATNAA50
SCHEMBL16289037	0.99	EP300 (0.44)	EP300KAT5CREBBPCHATNAA50

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2013100132-A1	PEPTIDE-COMPOUND CYCLIZATION METHOD	中外製薬株式会社 (JP)	2013-07-04	—	—	WO	disclosed