Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.43 |
| ▸ | PPARG | P37231 | 10/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 5/20 | 0.40 |
| ▸ | CTSK | P43235 | 5/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23157235 | 1.00 | PPARA (0.43) | PPARAPPARGPPARDCTSSCTSK | |
| SCHEMBL23157106 | 0.90 | CYP1A2 (0.39) | PPARAPPARGPPARDCTSSCTSK | |
| SCHEMBL15083181 | 0.90 | CYP1A2 (0.39) | PPARAPPARGPPARDCTSSCTSK | |
| SCHEMBL16310609 | 0.89 | PPARA (0.42) | PPARAPPARGPPARDCTSSCTSK | |
| SCHEMBL23056299 | 0.89 | PPARA (0.40) | PPARAPPARGPPARDCTSSCTSK | |
| SCHEMBL16574725 | 0.88 | PPARA (0.40) | PPARAPPARGPPARDCTSSCTSK | |
| SCHEMBL16289141 | 0.85 | PPARA (0.38) | PPARAPPARGPPARDCTSSCTSK | |
| SCHEMBL16289142 | 0.85 | PPARA (0.38) | PPARAPPARGPPARDCTSSCTSK | |
| SCHEMBL16289140 | 0.85 | PPARA (0.38) | PPARAPPARGPPARDCTSSCTSK | |
| SCHEMBL23157230 | 0.84 | PPARA (0.42) | PPARAPPARGPPARDCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2813512-A1 | PEPTIDE-COMPOUND CYCLIZATION METHOD | Chugai Seiyaku Kabushiki Kaisha (JP) | 2014-12-17 | — | — | EP | disclosed |
| WO-2013100132-A1 | PEPTIDE-COMPOUND CYCLIZATION METHOD | 中外製薬株式会社 (JP) | 2013-07-04 | — | — | WO | disclosed |