SCHEMBL15083585

CC(C)(C)OC(=O)N[C@@H](CCCNC(=O)OCc1ccccc1N=[N+]=[N-])C(=O)O[C@H]1[C@@H](O)[C@H](n2cnc3c(N)ncnc32)O[C@@H]1COP(=O)(O)O[C@H]1CC(n2ccc(N)nc2=O)O[C@@H]1COP(=O)(O)O

nearest known ligand 0.43

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	EP300	Q09472	4/20	0.43

▸	KAT5	Q92993	2/20	0.41

▸	CREBBP	Q92793	1/20	0.41

▸	ENPP1	P22413	1/20	0.40

▸	CHAT	P28329	2/20	0.40

▸	NAA50	Q9GZZ1	2/20	0.40

▸	AURKA	O14965	1/20	0.40

▸	KAT2B	Q92831	1/20	0.40

▸	RNASEL	Q05823	7/20	0.39

▸	TERT	O14746	1/20	0.39

▸	DOT1L	Q8TEK3	2/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL16288359	1.00	EP300 (0.43)	EP300KAT5CREBBPENPP1CHAT
SCHEMBL16288350	1.00	EP300 (0.43)	EP300KAT5CREBBPENPP1CHAT
SCHEMBL16288353	1.00	EP300 (0.43)	EP300KAT5CREBBPENPP1CHAT
SCHEMBL16568708	1.00	EP300 (0.43)	EP300KAT5CREBBPENPP1CHAT
SCHEMBL16288363	1.00	EP300 (0.43)	EP300KAT5CREBBPENPP1CHAT
SCHEMBL16288366	1.00	EP300 (0.43)	EP300KAT5CREBBPENPP1CHAT
SCHEMBL15083341	1.00	EP300 (0.43)	EP300KAT5CREBBPENPP1CHAT
SCHEMBL16288063	0.99	EP300 (0.43)	EP300KAT5CREBBPENPP1CHAT
SCHEMBL15083590	0.99	EP300 (0.43)	EP300KAT5CREBBPENPP1CHAT
SCHEMBL16574776	0.99	EP300 (0.43)	EP300KAT5CREBBPENPP1CHAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2013100132-A1	PEPTIDE-COMPOUND CYCLIZATION METHOD	中外製薬株式会社 (JP)	2013-07-04	—	—	WO	disclosed