Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 3/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | MPO | P05164 | 1/20 | 0.30 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.30 |
| ▸ | EED | O75530 | 1/20 | 0.30 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.30 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.30 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15065962 | 0.89 | ERN1 (0.35) | CYP11B1ALDH1A1KDM4EMAPTNPSR1 | |
| SCHEMBL30077989 | 0.89 | ERN1 (0.35) | CYP11B1ALDH1A1KDM4EMAPTNPSR1 | |
| SCHEMBL16072974 | 0.78 | KDM4E (0.41) | ALDH1A1KDM4E | |
| SCHEMBL24357962 | 0.78 | ERN1 (0.35) | ALDH1A1MAPTPLCG1CD274 | |
| SCHEMBL16072984 | 0.78 | SYK (0.34) | ALDH1A1KDM4EMAPTNPSR1TDP1 | |
| SCHEMBL16072973 | 0.77 | DPP4 (0.44) | ALDH1A1KDM4EMAPTNPSR1TDP1 | |
| SCHEMBL15068295 | 0.77 | CYP11B1 (0.32) | CYP11B1ALDH1A1CSF1RCD274SGMS2 | |
| SCHEMBL16072986 | 0.76 | KCNA5 (0.43) | PDE4B | |
| SCHEMBL21755850 | 0.75 | PPARA (0.30) | CSF1R | |
| SCHEMBL16072979 | 0.73 | CSF1R (0.34) | CSF1RSGMS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013102142-A1 | SUBSTITUTED BENZALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION | GLOBAL BLOOD THERAPEUTICS, INC. (US) | 2013-07-04 | — | — | WO | disclosed |